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Plasma Fractionation: An Essential Process in Modern Biotherapeutics
Plasma fractionation is a highly specialized biochemical process used to separate and extract valuable proteins from human blood plasma. These proteins play a critical role in treating a wide range of disorders, including immune deficiencies, bleeding disorders, and chronic inflammatory diseases. Because plasma contains numerous proteins with distinct biological functions, fractionation helps isolate each component in a pure and usable form, enabling the development of life-saving therapeutic products.
The process begins with the collection of plasma from donors through plasmapheresis or whole-blood donation. Once collected, the plasma undergoes rigorous testing to ensure safety and quality. This step is crucial because plasma-derived products must meet stringent standards to prevent contamination and guarantee patient safety. Only plasma that passes these safety checks moves forward to the fractionation stage.
One of the most widely used techniques in plasma fractionation is cold ethanol fractionation, originally developed…
